Environmental Mercury Release, Special education
rates, and autism disorders: an ecological study
Med Sci Monit. 2004 Mar;10(3):PI33-9. Epub 2004 Mar 1.
A comparative evaluation of the effects
of MMR immunization and mercury doses from thimerosal-containing
childhood vaccines on the population prevalence
President, MedCon, Inc, Silver Spring, MD, USA.
BACKGROUND: The purpose of the study was to evaluate
the effects of MMR immunization and mercury from
thimerosal-containing childhood vaccines on the prevalence
of autism. MATERIAL/METHODS: Evaluations of the Biological
Surveillance Summaries of the Centers for Disease
Control and Prevention (CDC), the U.S. Department
of Education datasets, and the CDC's yearly live
birth estimates were undertaken RESULTS: It was determined
that there was a close correlation between mercury
doses from thimerosal--containing childhood vaccines
and the prevalence of autism from the late 1980s
through the mid-1990s. In contrast, there was a potential
correlation between the number of primary pediatric
measles-containing vaccines administered and the
prevalence of autism during the 1980s. In addition,
it was found that there were statistically significant
odds ratios for the development of autism following
increasing doses of mercury from thimerosal-containing
vaccines (birth cohorts: 1985 and 1990-1995) in comparison
to a baseline measurement (birth cohort: 1984). The
contribution of thimerosal from childhood vaccines
(>50% effect) was greater than MMR vaccine on
the prevalence of autism observed in this study.
CONCLUSIONS: The results of this study agree with
a number of previously published studies. These studies
have shown that there is biological plausibility
and epidemiological evidence showing a direct relationship
between increasing doses of mercury from thimerosal-containing
vaccines and neurodevelopmental disorders, and measles-containing
vaccines and serious neurological disorders. It is
recommended that thimerosal be removed from all vaccines,
and additional research be undertaken to produce
a MMR vaccine with an improved safety profile.
PMID: 14976450 [PubMed - indexed for MEDLINE]
Pediatr Rehabil. 2003 Apr-Jun;6(2):97-102.
An assessment of the impact of thimerosal
on childhood neurodevelopmental disorders.
The Genetic Centers of America, 14 Redgate Court,
Silver Spring, MD 20905, USA.
The prevalence of autism in the US has risen from
1 in approximately 2500 in the mid-1980s to 1 in
approximately 300 children in the mid-1990s. The
purpose of this study was to evaluate whether mercury
from thimerosal in childhood vaccines contributed
to neurodevelopmental disorders. Neurodevelopmental
disorder dose-response curves for increasing mercury
doses of thimerosal in childhood vaccines were determined
based upon examination of the Vaccine Adverse Events
Reporting System (VAERS) database and the 2001 US'
Department of Education Report. The instantaneous
dosage of mercury children received in comparison
to the Food and Drug Administration (FDA)'s maximum
permissible dose for the oral ingestion of methylmercury
was also determined. The dose-response curves showed
increases in odds ratios of neurodevelopmental disorders
from both the VAERS and US Department of Education
data closely linearly correlated with increasing
doses of mercury from thimerosal-containing childhood
vaccines and that for overall odds ratios statistical
significance was achieved. Similar slopes and linear
regression coefficients for autism odds ratios in
VAERS and the US Department of Education data help
to mutually validate each other. Controls employed
in the VAERS and US Department of Education data
showed minimal biases. The evidence presented here
shows that the occurrence of neurodevelopmental disorders
following thimerosal-containing childhood vaccines
does not appear to be coincidental.
Int J Toxicol. 2003 Jul-Aug;22(4):277-85.
Reduced levels of mercury in first baby
haircuts of autistic children.
SafeMinds, Cambridge, Massachusetts, USA.
Reported rates of autism have increased sharply
in the United States and the United Kingdom. One
possible factor underlying these increases is increased
exposure to mercury through thimerosal-containing
vaccines, but vaccine exposures need to be evaluated
in the context of cumulative exposures during gestation
and early infancy. Differential rates of postnatal
mercury elimination may explain why similar gestational
and infant exposures produce variable neurological
effects. First baby haircut samples were obtained
from 94 children diagnosed with autism using Diagnostic
and Statistical Manual of Mental Disorders, 4th edition
(DSM IV) criteria and 45 age- and gender-matched
controls. Information on diet, dental amalgam fillings,
vaccine history, Rho D immunoglobulin administration,
and autism symptom severity was collected through
a maternal survey questionnaire and clinical observation.
Hair mercury levels in the autistic group were 0.47
ppm versus 3.63 ppm in controls, a significant difference.
The mothers in the autistic group had significantly
higher levels of mercury exposure through Rho D immunoglobulin
injections and amalgam fillings than control mothers.
Within the autistic group, hair mercury levels varied
significantly across mildly, moderately, and severely
autistic children, with mean group levels of 0.79,
0.46, and 0.21 ppm, respectively. Hair mercury levels
among controls were significantly correlated with
the number of the mothers' amalgam fillings and their
fish consumption as well as exposure to mercury through
childhood vaccines, correlations that were absent
in the autistic group. Hair excretion patterns among
autistic infants were significantly reduced relative
to control. These data cast doubt on the efficacy
of traditional hair analysis as a measure of total
mercury exposure in a subset of the population. In
light of the biological plausibility of mercury's
role in neurodevelopmental disorders, the present
study provides further insight into one possible
mechanism by which early mercury exposures could
increase the risk of autism.
PMID: 12933322 [PubMed - indexed for MEDLINE]
Med Hypotheses. 2001 Apr;56(4):462-71.
Autism: a novel form of mercury poisoning.
ARC Research, Cranford, New Jersey 07901, USA.
Autism is a syndrome characterized by impairments
in social relatedness and communication, repetitive
behaviors, abnormal movements, and sensory dysfunction.
Recent epidemiological studies suggest that autism
may affect 1 in 150 US children. Exposure to mercury
can cause immune, sensory, neurological, motor, and
behavioral dysfunctions similar to traits defining
or associated with autism, and the similarities extend
to neuroanatomy, neurotransmitters, and biochemistry.
Thimerosal, a preservative added to many vaccines,
has become a major source of mercury in children
who, within their first two years, may have received
a quantity of mercury that exceeds safety guidelines.
A review of medical literature and US government
data suggests that: (i) many cases of idiopathic
autism are induced by early mercury exposure from
thimerosal; (ii) this type of autism represents an
unrecognized mercurial syndrome; and (iii) genetic
and non-genetic factors establish a predisposition
whereby thimerosal's adverse effects occur only in
some children. Copyright 2001 Harcourt Publishers
Jeff Bradstreet has an excellent site with many
scientific research articles.
See his website for more: http://www.icdrc.org/research.html